Launching a ClickOnce application generates an error like one of the following when using Chrome.
Google has chosen to discontinue support for ClickOnce applications as per https://developer.chrome.com/extensions/npapi
To resolve this issue please launch the apps using Internet Explorer (IE) 10 or 11.
All apps launched via Chrome including the following.
Workflow Editor - all versions unless otherwise noted.
RDP connector - all versions unless otherwise noted.